WebNational Center for Biotechnology Information Web类型 ：长文. 作者机构 ：CMU. 方向 ：上下文. 研究背景 ：分析人工译员做翻译时使用什么样的上下文环境解决歧义问题，并研究模型关注的语境是否相似. 研究方法 ：（分析部分略） 在损失函数中加入注意力正则化，让模型学习的注意力向标注得到的注意力 ...

BLOC1S1/GCN5L1/BORCS1 is a critical mediator for the initiation …

WebOxidative stress-induced DNA damage, the senescence-associated secretory phenotype (SASP), and impaired autophagy all are general features of senescent cells. However, the cross-talk among these events and processes is not fully understood. Here, using NIH3T3 cells exposed to hydrogen peroxide stress, we show that stress-induced DNA damage … Web蛋白质翻译后修饰 (Protein translational modifications，PTMs) 通过功能基团或蛋白质的共价添加、调节亚基的蛋白水解切割或整个蛋白质的降解来增加蛋白质组的功能多样性。这些修饰包括磷酸化、糖基化、泛素化、亚硝基化、甲基化、乙酰化、脂质化和蛋白水解，几乎影响正常细胞生物学和发病机制的 ... main character in unbroken

phagolysosomal是什么意思，异噬溶酶体翻译-生物医药大词典

WebChronic or acute Dyn2 inhibition combined with nutrient deprivation stimulated the excessive tubulation of these autolysosomal compartments. Importantly, Dyn2 associated with these tubules along their length, and the tubules vesiculated and fragmented in the presence of functional Dyn2. These findings provide new evidence for the participation ... WebJun 26, 2014 · Author Summary Spinster homolog 1 (Spns1) in vertebrates, as well as Spinster (Spin) in Drosophila, is a hypothetical lysosomal H+-carbohydrate transporter, which functions at a late stage of autophagy. The Spin/Spns1 defect induces aberrant autolysosome formation that leads to embryonic senescence and accelerated aging … WebNov 26, 2024 · Autolysosomal degradation is the final step of autophagy, during which autolysosomal substrates are degraded by lysosomal acid hydrolases. These hydrolases, including proteases, ... main characteristics of amphibians