WebApr 14, 2024 · Research is currently focused on maximizing cancer cell death while minimizing harm to healthy cells. Gold nanoparticles (GNPs) have been extensively studied as a radiosensitizer to improve cancer cell death while sparing normal tissue. Previous research and simulations have demonstrated that the presence of a single GNP … WebApr 11, 2024 · Chithrani was awarded $200,000 to research a nanomedical approach to pancreatic-cancer radiation therapy. A second grant, to use radiation to trigger the release of LNP payloads only at tumor sites for head and neck carcinomas, is a collaboration with UBC molecular biologist Pieter Cullis—known for encapsulating m-RNA in LNPs for covid-19 ...
Devika Chithrani - University of Victoria
WebAug 26, 2024 · According to the global cancer observatory (GLOBOCAN), there are approximately 18 million new cancer cases per year worldwide. Cancer therapies are largely limited to surgery, radiotherapy, and chemotherapy. In radiotherapy and chemotherapy, the maximum tolerated dose is presently being used to treat cancer patients. The integrated … WebOct 22, 2024 · This roadmap outlines the potential roles of metallic nanoparticles (MNPs) in the field of radiation therapy. MNPs made up of a wide range of materials (from Titanium, Z = 22, to Bismuth, Z = 83) and a similarly wide spectrum of potential clinical applications, including diagnostic, therapeutic (radiation dose enhancers, hyperthermia inducers, drug … can an electrical panel be oversized
Modulation of nanoparticle uptake, intracellular distribution, and ...
WebApr 11, 2024 · A novel, simplistic approach for the synthesis of bio-mediated magnetite nanoparticles has been reported by employing an aqueous leaf extract of Elaeocarpus Sylvestris plant as a green source. The synthesized Elaeocarpus Sylvestris capped MNPs (ESMNPs) were investigated by different spectroscopic, electronic microscopic and … WebDr. Devika Chithrani is an associate professor in the Department of Physics at Ryerson University, Canada. She obtained her BSc from the University of Colombo, Sri Lanka … WebMar 1, 2006 · We investigated the intracellular uptake of different sized and shaped colloidal gold nanoparticles. We showed that kinetics and saturation concentrations are highly … can an electric field help create electricity