WebMar 1, 2024 · Acute kidney injury (AKI) is the main obstacle that limits the use of cisplatin in cancer treatment. Proton pump inhibitors (PPIs), the most commonly used class of medications for gastrointestinal complications in cancer patients, have been reported to cause adverse renal events. However, the effect of PPIs on cisplatin-induced AKI … Web42%–100% of patients depending on total cisplatin dose and length of exposure. Hypomagnesemia and renal magnesium wasting may persist for up to 6 years after …
Yale Scientists Seek to Shift Treatment of Kidney Damage
WebApr 11, 2024 · A U.S. judge on Friday suspended the U.S. Food and Drug Administration's 2000 approval of the drug, effectively banning sales while a case brought by anti-abortion groups before him continues in... WebThe pathophysiology of cisplatin-induced AKI involves proximal tubular injury, apoptosis, oxidative stress, inflammation, and vascular injury in the kidneys. At present, there are no effective... church ideas for easter sunday
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WebOct 13, 2024 · The role of DNA damage in cisplatin-induced CKD has also been investigated. In mice, multiple doses of 10 mg/kg cisplatin administered at 7-day … WebApr 11, 2024 · Abstract Number: 3130. Session Title: Developmental Therapeutics—Molecularly Targeted Agents and Tumor Biology. Date and Time: 6/3/2024, 8:00 AM-11:00 AM local time. ASCO will publish the official abstracts on its meeting website in advance of the ASCO Annual Meeting at 5:00 p.m. ET on Thursday, May 25, 2024. … WebApr 11, 2024 · The poster shows the final data from a phase 2 study evaluating the ability of the DRP ® companion diagnostic for cisplatin to prospectively identify patients with metastatic breast cancer that ... church ideas for valentine\u0027s day