The carbon tetrachloride model in mice
網頁Phenobarbital was administered once as a CYP inducer in the carbon tetrachloride-induced hepatitis model mice. The mRNA expression levels of Cyp3a11 and Cyp2b10 in the liver and small intestine were measured using reverse transcription polymerase chain …
The carbon tetrachloride model in mice
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網頁2024年4月3日 · Background The effects of hypoxia inducible factor-2α (HIF-2α) deficiency on liver fibrosis have not been demonstrated in a fibrosis model induced by carbon tetrachloride (CCl 4).We aimed to examine whether hepatocyte-specific HIF-2α deletion could ameliorate CCl 4-induced liver fibrosis in mice. 網頁2014年9月2日 · Detailed in this unit is a protocol for an experimental mouse model of HCC that arises in association with advanced liver fibrosis. The disease model is induced by a single injection of N -nitrosodiethylamine (DEN) followed by repeated administration of carbon tetrachloride (CCl 4 ).
網頁2015年4月1日 · Comparing distress of mouse models for liver damage. This study used receiver operating characteristic curve analysis to quantify the performance of burrowing … 網頁In hepatocytes, carbon tetrachloride (CCl 4) is transformed into trichloromethyl free radicals that can trigger cell damage that can lead to hepatocellular injuries such as fibrosis and cirrhosis (Zhao et al., 2024a ), resulting in oxidative stress, inflammation, and pyroptosis (Otrubova et al., 2024 ).
網頁2015年4月2日 · In the first section we focus on the carbon tetrachloride (CCl 4) model in mice, which is the toxic model of liver fibrosis induction most commonly used … 網頁2015年4月5日 · Abstract In addition to carbon tetrachloride (CCl4), thioacetamide (TAA) represents a second widely used model for the induction of experimental liver fibrosis, …
網頁Background: Several phyto-chemicals have been identified and suggested as potential therapeutic options for hepatotoxicity management. Objective: To assess the hepatoprotective effect of scopoletin, a pure phyto-chemical, in carbon tetrachloride (CCl 4)-induced hepatotoxicity model in Wistar rats. ...
網頁2024年11月11日 · Lophatherum gracile Bronghiart, used in traditional herbal medicine, has many biological properties including antiviral, antipyretic, antitumor, vasorelaxation, and neutrophilic inflammatory effects. However, its modulatory effects on bone metabolism have not been investigated previously. In this study, we examined the effects of a water extract … lampaannahka hanskat網頁2024年4月9日 · Download Citation On Apr 9, 2024, Chieri Fujino and others published Attenuation of phenobarbital‐induced cytochrome P450 expression in carbon … lampa animerad網頁2024年5月1日 · To establish hepatocarcinogenesis mouse model, a single dose of 25 mg/kg DEN (N-Nitrosodiethylamine, BioChem Partner, China) was i.p injected into both female and male WT and HKO mice ( N = 8 each group) at 14 days of age, followed by administration of 10% CCl 4 (v/v in corn oil, 8 ml/kg of body weight, Solarbio, China) … lampaannahkarukkaset網頁2024年9月25日 · This study evaluated the severity of liver fibrosis induction by intraperitoneal carbon tetrachloride (CCl 4) injections in mice. 29 male C57BL/6N mice … jesmar printing網頁2024年12月24日 · The protective effects of chlorogenic acid (CGA) against liver injury were evaluated by its reduction in carbon tetrachloride (CCl4)-induced hepatic damage in … jesmar para jugar網頁2015年4月1日 · In the first section we focus on the carbon tetrachloride (CCl4) model in mice, which is the toxic model of liver fibrosis induction most commonly used … jesmart網頁Carbon tetrachloride, also known by many other names (such as tetrachloromethane, also recognised by the IUPAC, carbon tet in the cleaning industry, Halon-104 in firefighting, and Refrigerant-10 in HVACR) is a chemical compound with the chemical formula CCl4. It is a colourless liquid with a "sweet" smell that can be detected at low levels. It ... lampaankare